For anyone using 32-bit PHP, files over 2GB can't be successfully ingested into Islandora. Note that the 64-bit versions of PHP for Windows still treat integers as 32-bit.
I have two pull requests pending, which offer a potential solution to this problem.
- Tuque 1.x: https://github.com/Islandora/tuque/pull/133
- Tuque 1.7: https://github.com/Islandora/tuque/pull/134
The only JIRA ticket I found that describes a similar issue is https://jira.duraspace.org/browse/ISLANDORA-1178, although the solution at the time was to update the documentation.